Search on: PROTEIN STRUCTURE, TERTIARY 
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Descriptor English:   Protein Structure, Tertiary 
Descriptor Spanish:   Estructura Terciaria de Proteína 
Descriptor Portuguese:   Estrutura Terciária de Proteína 
Synonyms English:   Protein Domains  
Tree Number:   G02.111.570.820.709.610
Definition English:   The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure. 
Indexing Annotation English:   IM general; coord NIM with specific protein (IM); PROTEIN MOTIFS see MOTIFS, AMINO ACID is available
History Note English:   93 
Allowable Qualifiers English:  
DE drug effects GE genetics
PH physiology RE radiation effects
Record Number:   30590 
Unique Identifier:   D017434 

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